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7 Additionally, the significant reduction in ICP noted at the early time points of 2.5 h and 24 h would have been too premature to be modulated by weight loss

The non-selectivity is both MT-2's strength (diverse pharmacology) and its weakness (unpredictable multi-system effects and increased side effect burden)

Goodman and Gillman's The Pharmacological Basis of Therapeutics, 9th ed